Course Description:
The implementation of Non-Coded amino acids to improve stability and function in therapeutic peptides is an active area of research. Many unnatural amino acid building blocks exist and are commercially available in quantities to enable SAR studies and early development. However, as scale is increased, the existing supplies may no longer be viable. This presentation will discuss the establishment of a supply chain for Fmoc alpha methyl quaternary amino acids. The focus will be on the development of manufacturing processes and an emphasis will be placed on specifications, key impurities, and manufacturing flexibility.
Who should participate:
- QA Manager
- QA Staff
- QC Chemist
- QC Manager
- R&D
- Regulatory
- Student
The live version of this recording took place on during the USP Workshop on Therapeutic Peptides and Oligonucleotides:
Regulations and Quality Standards on March 4, 2022
Access Duration:
Access to this course expires 60 days from the date of registration or until you mark the course ‘Complete’ – whichever occurs first.
Speaker:
Mark Kerr, Ph.D.
Sr. Research Scientist
Eli Lilly & Company