User-Determined Reporting Thresholds (On-Demand)

Curriculum

Course Description:
USP General Chapter <477> which becomes official on May 1, 2024, provides users a risk-based, flexible approach for determining the reporting thresholds for organic impurities, aligned with their product-specific implementation of a monograph test procedure. Detailed information in USP General Chapter <477> will be discussed on the topics below:

  • Alignment with International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use (ICH) Q3A and Q3B guidelines expectations
  • Product considerations
  • Routes of administration
  • Maximum daily dose

 Who should participate:

  • Users of chemically synthesized DS and/or DP Monographs
  • Analytical Chemists
  • Laboratory managers
  • QA/QC staff/managers
  • Managers
  • Directors
  • Production Managers
  • Compliance managers,
  • Compendial affairs personnel
  • All pharmaceutical professionals/academicians interested in organic impurities in DS and Drug Products 

The live version of this recording took place on January 31, 2024

Access Duration:
Access to this course expires 60 days from the date of registration or until you mark the course ‘Complete’ – whichever occurs first.

Speaker

Nick Garito
Senior Principal Scientist, Small Molecules, USP
B.Sc. degree in Chemistry from the Virginia Polytechnic Institute and State University

Antonio Hernandez-Cardoso
Senior Principal Scientist
General Chapters, USP

B.Sc. and M.Sc. degrees in Pharmaceutical Chemistry from the National Autonomous University of Mexico